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Restricted Diffusion in Bilateral Optic Nerves and Retinas as an Indicator of Venous Ischemia Caused by Cavernous Sinus Thrombophlebitis AJNR 27:1815-1816, Chen,J.S.,et al, 2006 See this aricle in Pubmed Article Abstract A 44-year-old man developed bilateral blindness following severe periorbital cellulites and pansinusitis. CT and MR imaging demonstrated bilateral cavernous sinus thrombosis. Diffusion-weighted imaging revealed reduced apparent diffusion coefficient in bilateral optic nerves, suggesting optic nerve ischemia caused by the cavernous sinus thrombophlebitis (CST). Following surgical debridement of pansinusitis, antimicrobial therapy, and anticoagulation, the patient recovered from the infectious episode but sustained permanent bilateral blindness. This case shows that both retinal and optic nerve ischemia can be the cause of blindness after CST. Arguments supporting an arterial-versus-venous origin for the ischemia are discussed.

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(click to filter results - removes previous filter) blindness cavernous sinus,thrombosis MRI,abnormal MRI,diffusion weighted optic nerve optic nerve,lesion of retinal lesion

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